Production of a Subunit Vaccine Candidate against Porcine Post-Weaning Diarrhea in High-Biomass Transplastomic Tobacco
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چکیده
منابع مشابه
Production of a Subunit Vaccine Candidate against Porcine Post-Weaning Diarrhea in High-Biomass Transplastomic Tobacco
Post-weaning diarrhea (PWD) in piglets is a major problem in piggeries worldwide and results in severe economic losses. Infection with Enterotoxigenic Escherichia coli (ETEC) is the key culprit for the PWD disease. F4 fimbriae of ETEC are highly stable proteinaceous polymers, mainly composed of the major structural subunit FaeG, with a capacity to evoke mucosal immune responses, thus demonstrat...
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Enterotoxigenic Escherichia coli (ETEC) strains are a major cause of diarrhea disease in humans and farm animals. E. coli fimbriae or colonization factor antigens (CFAs) and enterotoxins including heat-labile (LT) and heat-stable (ST) are the key virulence factors in ETEC diarrhea. Unlike fimbriae or LT, STa has not been much included as an antigen in vaccine development against ETEC diarrhea b...
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Porcine Post-Weaning Diarrhea (PWD) continues to be one of the most important swine diseases worldwide. Entero toxigenic Escherichia coli (ETEC) strains are the primary cause of PWD. The key virulence factors of ETEC in PWD are bacterial fimbrial adhesins and enterotoxins. Adhesions mediate ETEC bacteria initial attachment to pig epithelial cells and subsequent colonization at pig small intesti...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2012
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0042405